Spatial Resolution and Imaging Encoding fMRI Settings for Optimal Cortical and Subcortical Motor Somatotopy in the Human Brain.

Details

Serval ID
serval:BIB_AE2727BF9C23
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Spatial Resolution and Imaging Encoding fMRI Settings for Optimal Cortical and Subcortical Motor Somatotopy in the Human Brain.
Journal
Frontiers in neuroscience
Author(s)
Marquis R., Muller S., Lorio S., Rodriguez-Herreros B., Melie-Garcia L., Kherif F., Lutti A., Draganski B.
ISSN
1662-4548 (Print)
ISSN-L
1662-453X
Publication state
Published
Issued date
2019
Peer-reviewed
Oui
Volume
13
Pages
571
Language
english
Notes
Publication types: Journal Article
Publication Status: epublish
Abstract
There is much controversy about the optimal trade-off between blood-oxygen-level-dependent (BOLD) sensitivity and spatial precision in experiments on brain's topology properties using functional magnetic resonance imaging (fMRI). The sparse empirical evidence and regional specificity of these interactions pose a practical burden for the choice of imaging protocol parameters. Here, we test in a motor somatotopy experiment the impact of fMRI spatial resolution on differentiation between body part representations in cortex and subcortical structures. Motor somatotopy patterns were obtained in a block-design paradigm and visually cued movements of face, upper and lower limbs at 1.5, 2, and 3 mm spatial resolution. The degree of segregation of the body parts' spatial representations was estimated using a pattern component model. In cortical areas, we observed the same level of segregation between somatotopy maps across all three resolutions. In subcortical areas the degree of effective similarity between spatial representations was significantly impacted by the image resolution. The 1.5 mm 3D EPI and 3 mm 2D EPI protocols led to higher segregation between motor representations compared to the 2 mm 3D EPI protocol. This finding could not be attributed to differential BOLD sensitivity or delineation of functional areas alone and suggests a crucial role of the image encoding scheme - i.e., 2D vs. 3D EPI. Our study contributes to the field by providing empirical evidence about the impact of acquisition protocols for the delineation of somatotopic areas in cortical and sub-cortical brain regions.
Keywords
BOLD sensitivity, functional magnetic resonance imaging, image resolution, segregation, subcortical areas
Pubmed
Web of science
Open Access
Yes
Create date
18/07/2019 18:29
Last modification date
21/08/2019 6:32
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