[Functional renal investigation in Fabry disease]

Details

Serval ID
serval:BIB_ADA24B021ACB
Type
Article: article from journal or magazin.
Collection
Publications
Title
[Functional renal investigation in Fabry disease]
Journal
Presse Med
Author(s)
Froissart M., Benistan K., Germain  D. P.
ISSN-L
0755-4982 (Print) 0755-4982 (Linking)
Publication state
Published
Issued date
2007
Volume
36 Spec No 1
Pages
1S36-42
Notes
Froissart, Marc
Benistan, Karelle
Germain, Dominique P
fre
English Abstract
Review
France
2007/06/05 09:00
Presse Med. 2007 Mar;36 Spec No 1:1S36-42.
Abstract
Progressive decline in kidney function is a cardinal manifestation of Fbry disease. Proteinuria is usually the earliest biological marker of renal involvement. Renoprotection should associate both effective Enzyme Replocement Therapy (ERT) and non-specific anti-proteinuric therapy as recommended for all chronic kidney diseases. ERT has demonstrated high efficiency in the early clearing of globotriaosylceromide deposits, however the functional protecting effect on GFR decrease remains to be validated, especially in patients with CKD stage 3 or higher Estimation of GFR should be very cautious using creatinine based formulas, leading to measure GFR whenever possible in order to characterize the progression of CKD in Fabry patients.
Keywords
Fabry Disease/*complications, Humans, Kidney Diseases/diagnosis/*etiology/*prevention & control, Proteinuria/etiology/prevention & control, alpha-Galactosidase/therapeutic use
Create date
03/03/2016 17:49
Last modification date
21/08/2019 6:35
Usage data