Nocturnal penile tumescence and rigidity (NPTR) findings in spinal cord injured men with erectile dysfunction.

Details

Serval ID
serval:BIB_AD89C2F4BBE4
Type
Article: article from journal or magazin.
Collection
Publications
Title
Nocturnal penile tumescence and rigidity (NPTR) findings in spinal cord injured men with erectile dysfunction.
Journal
International Journal of Impotence Research
Author(s)
Schmid D.M., Hauri D., Schurch B.
ISSN
0955-9930 (Print)
ISSN-L
0955-9930
Publication state
Published
Issued date
2004
Volume
16
Number
5
Pages
433-440
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov'tPublication Status: ppublish
Abstract
This prospective study aimed at determining whether nocturnal penile tumescence and rigidity (NPTR) findings correlate to the neurologic disorders in spinal cord injured (SCI) patients suffering from erectile dysfunction (ED). A total of 25 acute SCI male patients with post-traumatic ED underwent neurological, electrophysiological and urodynamic examinations, respectively, as well as NPTR recordings. The mean value for rigidity (R), tumescence (T) and duration (D) during NTPR tests were 83.3%, 3.3 cm, 6.4 min in patients with a complete lesion above the sacral (S2-S4) spinal cord (n=10), 46.1%, 1.6 cm, 5.5 min in patients with a complete lesion involving the sacral metameres (n=5) and 89.8%, 3.8 cm, 29 min in patients with an incomplete suprasacral lesion (n=7). The differences among these groups were statistically significant (P<0.05). Patients with lesions involving both sacral and thoracolumbar spinal cord showed no erections (n=3). We found four NTPR patterns: (1) normal R and T, short D; (2) weak R and T, short D; (3) normal R, T and D; and (4) no erections, which can be assigned to different levels and completeness of spinal cord lesions. Nocturnal erections of normal quality need preservation of thoracolumbar and sacral neuronal control as well as partially intact connections of the spinal erection centres with brain areas responsible for sexual arousal.
Keywords
Adolescent, Adult, Alprostadil/administration & dosage, Alprostadil/pharmacology, Electromyography, Electrophysiology, Erectile Dysfunction/physiopathology, Humans, Injections, Male, Middle Aged, Neurologic Examination, Penile Erection/physiology, Penis, Reflex/physiology, Spinal Cord Injuries/physiopathology, Urodynamics/physiology, Vasodilator Agents/administration & dosage, Vasodilator Agents/pharmacology
Pubmed
Web of science
Open Access
Yes
Create date
05/11/2014 12:12
Last modification date
20/08/2019 15:17
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