Evolution of dosage compensation under sexual selection differs between X and Z chromosomes.

Details

Serval ID
serval:BIB_AD37B460C0EF
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Evolution of dosage compensation under sexual selection differs between X and Z chromosomes.
Journal
Nature Communications
Author(s)
Mullon C., Wright A.E., Reuter M., Pomiankowski A., Mank J.E.
ISSN
2041-1723 (Electronic)
ISSN-L
2041-1723
Publication state
Published
Issued date
2015
Peer-reviewed
Oui
Volume
6
Pages
7720
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: epublish
Abstract
Complete sex chromosome dosage compensation has more often been observed in XY than ZW species. In this study, using a population genetic model and the chicken transcriptome, we assess whether sexual conflict can account for this difference. Sexual conflict over expression is inevitable when mutation effects are correlated across the sexes, as compensatory mutations in the heterogametic sex lead to hyperexpression in the homogametic sex. Coupled with stronger selection and greater reproductive variance in males, this results in slower and less complete evolution of Z compared with X dosage compensation. Using expression variance as a measure of selection strength, we find that, as predicted by the model, dosage compensation in the chicken is most pronounced in genes that are under strong selection biased towards females. Our study explains the pattern of weak dosage compensation in ZW systems, and suggests that sexual selection plays a major role in shaping sex chromosome dosage compensation.
Keywords
Animals, Chickens, Dosage Compensation, Genetic/genetics, Evolution, Molecular, Female, Gene Expression, Gene Expression Profiling, Male, Selection, Genetic/genetics, Sex Chromosomes/genetics, X Chromosome, X Chromosome Inactivation
Pubmed
Web of science
Open Access
Yes
Create date
10/06/2015 14:18
Last modification date
20/08/2019 16:17
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