Infection prevention and control risk factors for SARS-CoV-2 infection in health workers: a global, multicentre case-control study.

Details

Serval ID
serval:BIB_AD0523D56913
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Infection prevention and control risk factors for SARS-CoV-2 infection in health workers: a global, multicentre case-control study.
Journal
The Journal of hospital infection
Author(s)
Cassini A., Yin M., Simniceanu A., Gon G., Cowling B.J., Allegranzi B.
Working group(s)
COVID-19 in Health Workers Collaborative Group
Contributor(s)
Pejic A., Turmukhambetova A., Omarkulov B., Carevic B., Mdziniso B., Ebrahim F.K., Habebe S., Conly J., Tsekrekos S., Pinchera B., Gentile I., Villari P., Poscia R., Lia L., Falasconi G., Torre G., Filon F.L., Porru S., Spiteri G., Vatcheva-Dobrevska R., Stefanowa P., Dicheva V., Markovic-Denic L., Akhmaltdinova L., Ciofi Degli Atti M.L., Marusic V., Nikolic V., Mioljevic V., Okwor T., Akande T., Ogboghodo E.O., Tyszkiewicz J., Placha G., Alrstom A., Abouharb R., Alzuhaily H., Tarif A.B., Bellizzi S., Ramadan M., Tsereteli D., Chakhunashvili G., Pashalishvili M., Raka L., Aregey A., Verovchuk B., Stetsyk V., Novak T., Hakim F., Mostafa Z., Shirin T., Adsul B.B., Ahmad M., Bhansali S., Bilimale A., Das P., Rahman M., Garat V.G., Kaur R., Kant S., Khapre M., George L.S., Narlawar U., Rathod P., Rathod S., Retnakumar C., Patel P.B., Sharma S., Saxena V., Tomy C., Wadhava S., Berba R.P., Therese G Virata M.P., Sandejas JCM
ISSN
1532-2939 (Electronic)
ISSN-L
0195-6701
Publication state
In Press
Peer-reviewed
Oui
Language
english
Notes
Publication types: Journal Article
Publication Status: aheadofprint
Abstract
Health workers were at higher risk for SARS-CoV-2 infection during the COVID-19 pandemic due to occupational risk factors. As part of the WHO Unity Studies initiative, we aimed to characterise these risk factors.
This global, multicentre, nested, case-control study was conducted in 121 healthcare facilities in 21 countries. Cases were health workers who tested positive for SARS-CoV-2 infection with a documented occupational exposure to COVID-19 patients in the 14 days pre-enrolment. Controls were enrolled from the same facility with a similar exposure but negative serology. Case and control status was confirmed with serological testing at baseline and after 3-4 weeks. Demographic and infection risk factor data were collected using structured questionnaires.
Between June 2020 and December 2021, data were obtained for 1213 cases and 1844 controls. SARS-CoV-2 infection risk was associated with non-adherence to personal protective equipment (PPE) guidelines (aOR 1·67 [95% CI 1·32-2·12]) and not consistently performing hand hygiene after patient contact (aOR 2·52 [1·72-3·68]). Direct close contact with COVID-19 patients was also associated with an increased risk, particularly during prolonged contact (>15 min.). Items associated with a lower risk were respirators during aerosol-generating procedures and gloves, gowns or coveralls during contact with contaminated materials/surfaces. No difference was observed among health workers using respirators versus surgical masks for routine care.
Appropriate implementation of infection prevention and control measures and PPE use remain a priority to protect health workers from SARS-CoV-2 infection.
Keywords
COVID-19, SARS-CoV-2, adherence, health workers, infection prevention and control, occupational risk factors, personal protective equipment
Pubmed
Open Access
Yes
Create date
30/09/2024 13:45
Last modification date
01/10/2024 7:07
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