Splenium of corpus callosum: patterns of interhemispheric interaction in children and adults.

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Serval ID
serval:BIB_ACF5C5FFAC7A
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Splenium of corpus callosum: patterns of interhemispheric interaction in children and adults.
Journal
Neural Plasticity
Author(s)
Knyazeva M.G.
ISSN
1687-5443 (Electronic)
Publication state
Published
Issued date
2013
Volume
2013
Pages
639430
Language
english
Notes
Publication types: Journal ArticlePublication Status: ppublish. PDF type: Review Article
Abstract
The splenium of the corpus callosum connects the posterior cortices with fibers varying in size from thin late-myelinating axons in the anterior part, predominantly connecting parietal and temporal areas, to thick early-myelinating fibers in the posterior part, linking primary and secondary visual areas. In the adult human brain, the function of the splenium in a given area is defined by the specialization of the area and implemented via excitation and/or suppression of the contralateral homotopic and heterotopic areas at the same or different level of visual hierarchy. These mechanisms are facilitated by interhemispheric synchronization of oscillatory activity, also supported by the splenium. In postnatal ontogenesis, structural MRI reveals a protracted formation of the splenium during the first two decades of human life. In doing so, the slow myelination of the splenium correlates with the formation of interhemispheric excitatory influences in the extrastriate areas and the EEG synchronization, while the gradual increase of inhibitory effects in the striate cortex is linked to the local inhibitory circuitry. Reshaping interactions between interhemispherically distributed networks under various perceptual contexts allows sparsification of responses to superfluous information from the visual environment, leading to a reduction of metabolic and structural redundancy in a child's brain.
Pubmed
Web of science
Open Access
Yes
Create date
12/04/2013 17:59
Last modification date
20/08/2019 15:16
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