The pseudo-high-risk prevention strategy

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Serval ID
serval:BIB_ACE4D74F2681
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
The pseudo-high-risk prevention strategy
Journal
International Journal of Epidemiology
Author(s)
Chiolero A., Paradis G., Paccaud F.
ISSN
1464-3685 (Electronic)
ISSN-L
0300-5771
Publication state
Published
Issued date
2015
Peer-reviewed
Oui
Volume
44
Number
5
Pages
1469-1473
Language
english
Abstract
Key Messages: A fundamental failure of high-risk prevention strategies is their inability to prevent disease in the large part of the population at a relatively small average risk and from which most cases of diseases originate. The development of individual predictive medicine and the widening of high-risk categories for numerous (chronic) conditions lead to the application of pseudo-high-risk prevention strategies. Widening the criteria justifying individual preventive interventions and the related pseudo-high-risk strategies lead to treating, individually, ever healthier and larger strata of the population. The pseudo-high-risk prevention strategies raise similar problems compared with high-risk strategies, however on a larger scale and without any of the benefit of population-based strategies.
Some 30 years ago, the strengths and weaknesses of population-based and high-risk prevention strategies were brilliantly delineated by Geoffrey Rose in several seminal publications (Table 1).1,2 His work had major implications not only for epidemiology and public health but also for clinical medicine. In particular, Rose demonstrated the fundamental failure of high-risk prevention strategies, that is, by missing a large number of preventable cases.
Pubmed
Web of science
Open Access
Yes
Create date
25/06/2015 14:05
Last modification date
25/09/2019 7:10
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