Allergologie-immunologie Clinique. De l’espoir pour les pathologies inflammatoires chroniques : l’antirécepteur de l’IL-6 tocilizumab [Hope for chronic inflammatory diseases : the anti-IL-6 receptor monoclonal antibody tocilizumab]

Details

Serval ID
serval:BIB_AC5DE6E8643E
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Allergologie-immunologie Clinique. De l’espoir pour les pathologies inflammatoires chroniques : l’antirécepteur de l’IL-6 tocilizumab [Hope for chronic inflammatory diseases : the anti-IL-6 receptor monoclonal antibody tocilizumab]
Journal
Revue medicale suisse
Author(s)
Spertini F.
ISSN
1660-9379 (Print)
ISSN-L
1660-9379
Publication state
Published
Issued date
11/01/2017
Peer-reviewed
Oui
Volume
13
Number
544-545
Pages
20-22
Language
french
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Abstract
Vasculitis like Horton's disease, some autoinflammatory syndromes (Behcet's, Still's diseases) often require long term treatment with steroids, and therefore are associated with non acceptable adverse events, especially when resistant to treatment. Recently, a number of controlled prospective clinical trials are supporting the interest of the anti-IL-6 receptor monoclonal antibody tocilizumab in these chronic inflammatory conditions et may soon be recognized as second intention therapeutic approach.

Keywords
Antibodies, Monoclonal/therapeutic use, Antibodies, Monoclonal, Humanized/therapeutic use, Chronic Disease, Humans, Inflammation/drug therapy, Inflammation/immunology, Receptors, Interleukin-6/antagonists & inhibitors, Receptors, Interleukin-6/immunology, Vasculitis/drug therapy
Pubmed
Create date
18/08/2017 14:55
Last modification date
20/08/2019 15:16
Usage data