Towards a new mapping of brain cortex function.

Details

Serval ID
serval:BIB_AC4A855C3698
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Title
Towards a new mapping of brain cortex function.
Journal
Cerebrovascular Diseases
Author(s)
Ward N.S., Frackowiak R.S.
ISSN
1015-9770 (Print)
ISSN-L
1015-9770
Publication state
Published
Issued date
2004
Volume
17 Suppl 3
Pages
35-38
Language
english
Notes
Publication types: Journal Article ; ReviewPublication Status: ppublish
Abstract
The aim of imaging neuroscience is to describe the functional organization of human brain at the level of large neuronal groupings, networks and systems. The systems level of description addresses how integrated brain functions are embodied in the physical structure of the brain. Magnetic resonance imaging is currently the technique of choice for the study of cerebral structure-function relationships and the analysis of structural and functional brain images can now be carried out automatically using statistical parametric mapping. The resultant ability to perform clinical-functional-anatomical correlative studies with complete objectivity and unparalleled sensitivity is providing powerful new opportunities for studying the relationship between structure and function, and how these parameters interact with pathology. One of the most exciting and dramatic observations to come from human brain mapping has been the dynamic plasticity of function in both normal brains and the brains of patients with neurological and neuropsychiatric disorders. Recent activation studies have provided interesting information about the brain's capacity to reorganize after injury and in association with practice and learning. The emerging studies of brain plasticity and its modulation by drugs and other therapies indicate potentially useful approaches to the rehabilitation of adults with brain damage, including damage resulting from cerebral ischaemia. Brain maps must therefore be viewed as dynamic, changing with development, disease progression, normal learning and in parallel with the recovery of function after acute injury. The dynamic plasticity of functional brain maps provides an exciting opportunity to study these processes.
Keywords
Brain Mapping, Cerebral Cortex/anatomy & histology, Cerebral Cortex/pathology, Humans, Magnetic Resonance Imaging, Stroke/pathology, Stroke/physiopathology
Pubmed
Web of science
Create date
11/09/2011 18:34
Last modification date
20/08/2019 15:16
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