A global analysis of Y-chromosomal haplotype diversity for 23 STR loci.

Details

Serval ID
serval:BIB_AB35A4C32A84
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
A global analysis of Y-chromosomal haplotype diversity for 23 STR loci.
Journal
Forensic Science International. Genetics
Author(s)
Purps J., Siegert S., Willuweit S., Nagy M., Alves C., Salazar R., Angustia S.M., Santos L.H., Anslinger K., Bayer B., Ayub Q., Wei W., Xue Y., Tyler-Smith C., Bafalluy M.B., Martínez-Jarreta B., Egyed B., Balitzki B., Tschumi S., Ballard D., Court D.S., Barrantes X., Bäßler G., Wiest T., Berger B., Niederstätter H., Parson W., Davis C., Budowle B., Burri H., Borer U., Koller C., Carvalho E.F., Domingues P.M., Chamoun W.T., Coble M.D., Hill C.R., Corach D., Caputo M., D'Amato M.E., Davison S., Decorte R., Larmuseau M.H., Ottoni C., Rickards O., Lu D., Jiang C., Dobosz T., Jonkisz A., Frank W.E., Furac I., Gehrig C., Castella V., Grskovic B., Haas C., Wobst J., Hadzic G., Drobnic K., Honda K., Hou Y., Zhou D., Li Y., Hu S., Chen S., Immel U.D., Lessig R., Jakovski Z., Ilievska T., Klann A.E., García C.C., de Knijff P., Kraaijenbrink T., Kondili A., Miniati P., Vouropoulou M., Kovacevic L., Marjanovic D., Lindner I., Mansour I., Al-Azem M., Andari A.E., Marino M., Furfuro S., Locarno L., Martín P., Luque G.M., Alonso A., Miranda L.S., Moreira H., Mizuno N., Iwashima Y., Neto R.S., Nogueira T.L., Silva R., Nastainczyk-Wulf M., Edelmann J., Kohl M., Nie S., Wang X., Cheng B., Núñez C., Pancorbo M.M., Olofsson J.K., Morling N., Onofri V., Tagliabracci A., Pamjav H., Volgyi A., Barany G., Pawlowski R., Maciejewska A., Pelotti S., Pepinski W., Abreu-Glowacka M., Phillips C., Cárdenas J., Rey-Gonzalez D., Salas A., Brisighelli F., Capelli C., Toscanini U., Piccinini A., Piglionica M., Baldassarra S.L., Ploski R., Konarzewska M., Jastrzebska E., Robino C., Sajantila A., Palo J.U., Guevara E., Salvador J., Ungria M.C., Rodriguez J.J., Schmidt U., Schlauderer N., Saukko P., Schneider P.M., Sirker M., Shin K.J., Oh Y.N., Skitsa I., Ampati A., Smith T.G., Calvit L.S., Stenzl V., Capal T., Tillmar A., Nilsson H., Turrina S., De Leo D., Verzeletti A., Cortellini V., Wetton J.H., Gwynne G.M., Jobling M.A., Whittle M.R., Sumita D.R., Wolańska-Nowak P., Yong R.Y., Krawczak M., Nothnagel M., Roewer L.
ISSN
1878-0326 (Electronic)
ISSN-L
1872-4973
Publication state
Published
Issued date
2014
Peer-reviewed
Oui
Volume
12
Pages
12-23
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Abstract
In a worldwide collaborative effort, 19,630 Y-chromosomes were sampled from 129 different populations in 51 countries. These chromosomes were typed for 23 short-tandem repeat (STR) loci (DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS385ab, DYS437, DYS438, DYS439, DYS448, DYS456, DYS458, DYS635, GATAH4, DYS481, DYS533, DYS549, DYS570, DYS576, and DYS643) and using the PowerPlex Y23 System (PPY23, Promega Corporation, Madison, WI). Locus-specific allelic spectra of these markers were determined and a consistently high level of allelic diversity was observed. A considerable number of null, duplicate and off-ladder alleles were revealed. Standard single-locus and haplotype-based parameters were calculated and compared between subsets of Y-STR markers established for forensic casework. The PPY23 marker set provides substantially stronger discriminatory power than other available kits but at the same time reveals the same general patterns of population structure as other marker sets. A strong correlation was observed between the number of Y-STRs included in a marker set and some of the forensic parameters under study. Interestingly a weak but consistent trend toward smaller genetic distances resulting from larger numbers of markers became apparent.
Keywords
AMOVA, Database, Discriminatory power, Gene diversity, Population structure, Genetics, Forensic Medicine
Pubmed
Web of science
Open Access
Yes
Create date
26/05/2014 7:43
Last modification date
20/08/2019 15:15
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