Tremor revisited: treatment of PD tremor.

Details

Serval ID
serval:BIB_AA927961E8BA
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Tremor revisited: treatment of PD tremor.
Journal
Parkinsonism and Related Disorders
Author(s)
Jiménez M.C., Vingerhoets F.J.
ISSN
1873-5126 (Electronic)
ISSN-L
1353-8020
Publication state
Published
Issued date
2012
Peer-reviewed
Oui
Volume
18
Number
Suppl 1
Pages
S93-S95
Language
english
Notes
Publication types: Journal Article ; Review
Abstract
Parkinsonian tremor is among the most emblematic medical signs and is one of the cardinal manifestations of Parkinson's disease (PD). Its semiology has been extensively addressed by ancient and contemporary medical literature, but more attention has been dedicated to its medical treatment in the past than nowadays. Among the hundreds of studies performed to determine the value of medical and surgical approaches on motor and non motor signs of PD, only a minority specifically considered effect on tremor as an efficacy outcome. Current available guidelines for PD treatment include attempts to specifically address tremor treatment but stress the low level of evidences available. In these conditions, with its still poorly understood pathophysiological basis and variable clinical expression PD tremor treatment is a clinical challenge. Only surgery (lesion or high frequency stimulation) of discrete deep brain targets consistently provides symptomatic long lasting alleviation. Through revision of contemporary scientific evidence, the purpose of this paper is to offer a systematic pragmatic approach to symptomatic management of tremor as one of the distinctive signs of PD that may generate substantial disability.
Keywords
Animals, Antiparkinson Agents/therapeutic use, Electric Stimulation Therapy/methods, Electric Stimulation Therapy/trends, Humans, Parkinson Disease/diagnosis, Parkinson Disease/epidemiology, Radiosurgery/methods, Radiosurgery/trends, Treatment Outcome, Tremor/diagnosis, Tremor/epidemiology
Pubmed
Create date
20/09/2012 21:25
Last modification date
20/08/2019 15:14
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