FXYD7, the first brain- and isoform-specific regulator of Na,K-ATPase: biosynthesis and function of its posttranslational modifications

Details

Serval ID
serval:BIB_A9C8042C9C6E
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
FXYD7, the first brain- and isoform-specific regulator of Na,K-ATPase: biosynthesis and function of its posttranslational modifications
Journal
Annals of the New York Academy of Sciences
Author(s)
Crambert  G., Beguin  P., Uldry  M., Monnet-Tschudi  F., Horisberger  J. D., Garty  H., Geering  K.
ISSN
0077-8923 (Print)
Publication state
Published
Issued date
04/2003
Volume
986
Pages
444-8
Notes
Journal Article
Research Support, Non-U.S. Gov't --- Old month value: Apr
Abstract
The FXYD protein family has recently been defined as a result of the search for homologues of the Na,K-ATPase gamma subunit, CHIF, and phospholemman in EST and gene data banks. FXYD7 has been seen to have a role as a brain- and isozyme-specific regulator of Na/K-ATPase. In this study, the biosynthesis, membrane topology, nature, and role of the processing of FXYD7 are investigated.
Keywords
Animals Brain/metabolism Kinetics Membrane Glycoproteins/*metabolism Na(+)-K(+)-Exchanging ATPase/*biosynthesis Nerve Tissue Proteins/*metabolism Protein Isoforms/metabolism *Protein Processing, Post-Translational
Pubmed
Web of science
Create date
24/01/2008 12:28
Last modification date
20/08/2019 15:14
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