Better Pandemic Influenza Preparedness through Adjuvant Technology Transfer: Challenges and Lessons Learned.
Details
Serval ID
serval:BIB_A932D62586EB
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Better Pandemic Influenza Preparedness through Adjuvant Technology Transfer: Challenges and Lessons Learned.
Journal
Vaccines
ISSN
2076-393X (Print)
ISSN-L
2076-393X
Publication state
Published
Issued date
05/05/2021
Peer-reviewed
Oui
Volume
9
Number
5
Pages
461
Language
english
Notes
Publication types: Journal Article ; Review
Publication Status: epublish
Publication Status: epublish
Abstract
Adequate global vaccine coverage during an influenza pandemic is essential to mitigate morbidity, mortality, and economic impact. Vaccine development and production needs to be sufficient to meet a vast global demand, requiring international cooperation and local vaccine production capacity, especially in resource-constrained countries. The use of adjuvants is one approach to augment the number of available vaccine doses and to overcome potential vaccine shortages. Appropriately selected adjuvant technologies can decrease the amount of vaccine antigen required per dose, may broaden or lengthen the conferred protection against disease, and may even allow protective single-dose vaccination. Here we describe a technology transfer collaboration between Switzerland and Indonesia that led to the establishment of a vaccine formulation platform in Surabaya which involved the transfer of equipment and expertise to enable research and development of adjuvanted vaccine formulations and delivery systems. This new Indonesian capability aims to facilitate local and regional access to know-how relating to adjuvanted vaccine formulations, thus promoting their application to local vaccine developers. In this review, we aim to share the "lessons learned" from this project to both support and inspire future scientific collaborations of a similar nature.
Keywords
adjuvanted vaccines, global health, influenza, lessons learned, pandemic preparedness, technology transfer
Pubmed
Web of science
Open Access
Yes
Create date
14/06/2021 14:13
Last modification date
20/01/2025 15:05