Consortium neuroscience of attention deficit/hyperactivity disorder and autism spectrum disorder: The ENIGMA adventure.

Details

Serval ID
serval:BIB_A7D46CCED891
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Consortium neuroscience of attention deficit/hyperactivity disorder and autism spectrum disorder: The ENIGMA adventure.
Journal
Human brain mapping
Author(s)
Hoogman M., van Rooij D., Klein M., Boedhoe P., Ilioska I., Li T., Patel Y., Postema M.C., Zhang-James Y., Anagnostou E., Arango C., Auzias G., Banaschewski T., Bau CHD, Behrmann M., Bellgrove M.A., Brandeis D., Brem S., Busatto G.F., Calderoni S., Calvo R., Castellanos F.X., Coghill D., Conzelmann A., Daly E., Deruelle C., Dinstein I., Durston S., Ecker C., Ehrlich S., Epstein J.N., Fair D.A., Fitzgerald J., Freitag C.M., Frodl T., Gallagher L., Grevet E.H., Haavik J., Hoekstra P.J., Janssen J., Karkashadze G., King J.A., Konrad K., Kuntsi J., Lazaro L., Lerch J.P., Lesch K.P., Louza M.R., Luna B., Mattos P., McGrath J., Muratori F., Murphy C., Nigg J.T., Oberwelland-Weiss E., O'Gorman Tuura R.L., O'Hearn K., Oosterlaan J., Parellada M., Pauli P., Plessen K.J., Ramos-Quiroga J.A., Reif A., Reneman L., Retico A., Rosa PGP, Rubia K., Shaw P., Silk T.J., Tamm L., Vilarroya O., Walitza S., Jahanshad N., Faraone S.V., Francks C., van den Heuvel O.A., Paus T., Thompson P.M., Buitelaar J.K., Franke B.
ISSN
1097-0193 (Electronic)
ISSN-L
1065-9471
Publication state
In Press
Peer-reviewed
Oui
Language
english
Notes
Publication types: Journal Article ; Review
Publication Status: aheadofprint
Abstract
Neuroimaging has been extensively used to study brain structure and function in individuals with attention deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) over the past decades. Two of the main shortcomings of the neuroimaging literature of these disorders are the small sample sizes employed and the heterogeneity of methods used. In 2013 and 2014, the ENIGMA-ADHD and ENIGMA-ASD working groups were respectively, founded with a common goal to address these limitations. Here, we provide a narrative review of the thus far completed and still ongoing projects of these working groups. Due to an implicitly hierarchical psychiatric diagnostic classification system, the fields of ADHD and ASD have developed largely in isolation, despite the considerable overlap in the occurrence of the disorders. The collaboration between the ENIGMA-ADHD and -ASD working groups seeks to bring the neuroimaging efforts of the two disorders closer together. The outcomes of case-control studies of subcortical and cortical structures showed that subcortical volumes are similarly affected in ASD and ADHD, albeit with small effect sizes. Cortical analyses identified unique differences in each disorder, but also considerable overlap between the two, specifically in cortical thickness. Ongoing work is examining alternative research questions, such as brain laterality, prediction of case-control status, and anatomical heterogeneity. In brief, great strides have been made toward fulfilling the aims of the ENIGMA collaborations, while new ideas and follow-up analyses continue that include more imaging modalities (diffusion MRI and resting-state functional MRI), collaborations with other large databases, and samples with dual diagnoses.
Keywords
ADHD, ASD, ENIGMA, cortex, neuroimaging, subcortical volumes
Pubmed
Web of science
Open Access
Yes
Create date
14/06/2020 20:39
Last modification date
30/01/2021 7:26
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