The endoplasmic reticulum: a sensor of cellular stress that modulates immune responses.

Details

Serval ID
serval:BIB_A6EFFA30B665
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
The endoplasmic reticulum: a sensor of cellular stress that modulates immune responses.
Journal
Microbes and Infection
Author(s)
Martinon F.
ISSN
1769-714X (Electronic)
ISSN-L
1286-4579
Publication state
Published
Issued date
2012
Volume
14
Number
14
Pages
1293-1300
Language
english
Abstract
Many inflammatory and infectious diseases are characterized by the activation of signaling pathways steaming from the endoplasmic reticulum (ER). These pathways, primarily associated with loss of ER homeostasis, are emerging as key regulators of inflammation and infection. Recent advances shed light on the mechanisms linking ER-stress and immune responses.
Keywords
ER-stress, IRE1, XBP1, TLR, Innate immunity
Pubmed
Web of science
Create date
22/01/2013 9:22
Last modification date
20/08/2019 16:11
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