Resting-State Activity in High-Order Visual Areas as a Window into Natural Human Brain Activations.

Details

Serval ID
serval:BIB_A5957A28D89E
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Resting-State Activity in High-Order Visual Areas as a Window into Natural Human Brain Activations.
Journal
Cerebral cortex
Author(s)
Strappini F., Wilf M., Karp O., Goldberg H., Harel M., Furman-Haran E., Golan T., Malach R.
ISSN
1460-2199 (Electronic)
ISSN-L
1047-3211
Publication state
Published
Issued date
14/08/2019
Peer-reviewed
Oui
Volume
29
Number
9
Pages
3618-3635
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
A major limitation of conventional human brain research has been its basis in highly artificial laboratory experiments. Due to technical constraints, little is known about the nature of cortical activations during ecological real life. We have previously proposed the "spontaneous trait reactivation (STR)" hypothesis arguing that resting-state patterns, which emerge spontaneously in the absence of external stimulus, reflect the statistics of habitual cortical activations during real life. Therefore, these patterns can serve as a window into daily life cortical activity. A straightforward prediction of this hypothesis is that spontaneous patterns should preferentially correlate to patterns generated by naturalistic stimuli compared with artificial ones. Here we targeted high-level category-selective visual areas and tested this prediction by comparing BOLD functional connectivity patterns formed during rest to patterns formed in response to naturalistic stimuli, as well as to more artificial category-selective, dynamic stimuli. Our results revealed a significant correlation between the resting-state patterns and functional connectivity patterns generated by naturalistic stimuli. Furthermore, the correlations to naturalistic stimuli were significantly higher than those found between resting-state patterns and those generated by artificial control stimuli. These findings provide evidence of a stringent link between spontaneous patterns and the activation patterns during natural vision.
Keywords
free viewing, movie, ventral occipital–temporal cortex, naturalistic scenes, visual cortex
Pubmed
Web of science
Create date
13/11/2018 12:47
Last modification date
05/01/2020 6:18
Usage data