Therapeutic nanoparticles in clinics and under clinical evaluation.

Details

Serval ID
serval:BIB_A4D26E191D54
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Therapeutic nanoparticles in clinics and under clinical evaluation.
Journal
Nanomedicine
Author(s)
Schütz C.A., Juillerat-Jeanneret L., Mueller H., Lynch I., Riediker Michael
Working group(s)
NanoImpactNet Consortium
ISSN
1748-6963 (Electronic)
ISSN-L
1743-5889
Publication state
Published
Issued date
03/2013
Peer-reviewed
Oui
Volume
8
Number
3
Pages
449-467
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't ; Review
Publication Status: ppublish
Abstract
This article reviews nanoparticulate-chemotherapeutic systems that have been developed for human therapy, considering the components of the nanoparticles, the therapeutic agents associated with the nanoparticles and the clinical indications these therapeutic nanoparticles have been developed for. In this evaluation we have put into perspective the types of nanomaterials and their therapeutic indications. We have reviewed the nanoparticulate-chemotherapeutic systems that have been published, approved and marketed and that are currently in clinical use. We have also analyzed the nanoparticulate-chemotherapeutic systems that are in clinical trials and under preclinical development.

Keywords
Clinical Trials as Topic, Drug Delivery Systems/adverse effects, Drug Evaluation, Preclinical, Drug Therapy, Gold/adverse effects, Gold/chemistry, Gold/therapeutic use, Humans, Metal Nanoparticles/adverse effects, Metal Nanoparticles/therapeutic use
Pubmed
Web of science
Create date
28/03/2013 16:23
Last modification date
20/08/2019 15:10
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