La deuxième vie de ta rifampicine [The "second life" of rifampicin]

Details

Serval ID
serval:BIB_A47372B79192
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
La deuxième vie de ta rifampicine [The "second life" of rifampicin]
Journal
Revue medicale suisse
Author(s)
Stettler R., Trampuz A.
ISSN
1660-9379 (Print)
ISSN-L
1660-9379
Publication state
Published
Issued date
19/03/2014
Peer-reviewed
Oui
Volume
10
Number
422
Pages
670-672
Language
french
Notes
Publication types: English Abstract ; Journal Article ; Review
Publication Status: ppublish
Abstract
Despite it was initially used and was restricted mainly for the treatment of tuberculosis, rifampicin gained in past years interest for the treatment of infections associated with prosthetic devices. Rifampicin has an excellent tissue penetration and a unique activity on bacteria in biofilms growing on the surface of prosthetic devices. The rapid emergence of resistance in bacteria constitutes the Achilles' heel and therefore rifampicin should be used with caution. This review addresses the mode of action of rifampicin and describes possible pitfalls of its use.
Keywords
Anti-Bacterial Agents/pharmacology, Anti-Bacterial Agents/therapeutic use, Humans, Prosthesis-Related Infections/drug therapy, Rifampin/pharmacology, Rifampin/therapeutic use
Pubmed
Create date
17/02/2015 10:35
Last modification date
23/01/2024 7:14
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