An Interactive Cluster Heat Map to Visualize and Explore Multidimensional Metabolomic Data.

Details

Serval ID
serval:BIB_A3CFA7FCD6FD
Type
Article: article from journal or magazin.
Collection
Publications
Title
An Interactive Cluster Heat Map to Visualize and Explore Multidimensional Metabolomic Data.
Journal
Metabolomics
Author(s)
Ivanisevic J., Benton P.H., Rinehart D., Epstein A., Kurczy M.E., Boska M.D., Gendelman H.E., Siuzdak G.
ISSN
1573-3882 (Print)
Publication state
Published
Issued date
2015
Peer-reviewed
Oui
Volume
11
Number
4
Pages
1029-1034
Language
english
Abstract
Heat maps are a commonly used visualization tool for metabolomic data where the relative abundance of ions detected in each sample is represented with color intensity. A limitation of applying heat maps to global metabolomic data, however, is the large number of ions that have to be displayed and the lack of information provided about important metabolomic parameters such as m/z and retention time. Here we address these challenges by introducing the interactive cluster heat map in the data-processing software XCMS Online. XCMS Online (xcmsonline.scripps.edu) is a cloud-based informatic platform designed to process, statistically evaluate, and visualize mass-spectrometry based metabolomic data. An interactive heat map is provided for all data processed by XCMS Online. The heat map is clickable, allowing users to zoom and explore specific metabolite metadata (EICs, Box-and-whisker plots, mass spectra) that are linked to the METLIN metabolite database. The utility of the XCMS interactive heat map is demonstrated on metabolomic data set generated from different anatomical regions of the mouse brain.
Pubmed
Create date
06/06/2016 22:20
Last modification date
20/08/2019 16:09
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