Scattering of repetitive DNA sequences in the albumin and vitellogenin gene loci of Xenopus laevis.

Details

Serval ID
serval:BIB_A375A7870C72
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Scattering of repetitive DNA sequences in the albumin and vitellogenin gene loci of Xenopus laevis.
Journal
Nucleic Acids Research
Author(s)
Ryffel G.U., Muellener D.B., Gerber-Huber S., Wyler T., Wahli W.
ISSN
0305-1048[print], 0305-1048[linking]
Publication state
Published
Issued date
11/1983
Volume
11
Number
22
Pages
7701-7716
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Abstract
We have analyzed middle repetitive DNA in the albumin and vitellogenin gene families of Xenopus laevis. Mapping specific repetitive DNA sequences derived from introns of the A1 vitellogenin gene reveals that these sequences are scattered within and around the four vitellogenin genes (A1, A2, B1 and B2) and the two albumin genes (74 kd and 68 kd). Three repetitive DNA elements present in the A1 vitellogenin transcriptional unit are also located in introns of the 74 kd albumin gene. This apparently random distribution of middle repetitive DNA in the two gene families suggests that the analyzed sequences are not involved in gene regulation, but rather that they might represent unstable genetic elements. This hypothesis is further supported by the finding that size polymorphism in the A1 vitellogenin gene and in the 74 kd albumin gene is correlated with the presence or absence of repetitive DNA.
Keywords
Animals, Base Composition, Cloning, Molecular, DNA/genetics, Genes, Lipoproteins/genetics, Nucleic Acid Hybridization, Repetitive Sequences, Nucleic Acid, Serum Albumin/genetics, Vitellogenins/genetics, Xenopus
Pubmed
Web of science
Create date
24/01/2008 16:04
Last modification date
20/08/2019 15:09
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