Treatment of the N0 neck during salvage surgery after radiotherapy of head and neck squamous cell carcinoma.

Details

Serval ID
serval:BIB_A28DB213F1B2
Type
Article: article from journal or magazin.
Collection
Publications
Title
Treatment of the N0 neck during salvage surgery after radiotherapy of head and neck squamous cell carcinoma.
Journal
Head and Neck
Author(s)
Temam S., Koka V., Mamelle G., Julieron M., Carmantrant R., Marandas P., Janot F., Bourhis J., Luboinski B.
ISSN
1043-3074 (Print)
ISSN-L
1043-3074
Publication state
Published
Issued date
2005
Volume
27
Number
8
Pages
653-658
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't Publication Status: ppublish
Abstract
BACKGROUND: The morbidity and mortality rates of salvage surgery in patients with local recurrence of head and neck squamous cell carcinoma (HNSCC) after radiotherapy are high. The aim of this study was to determine the rate of occult neck node metastasis and the surgical morbidity of patients after salvage surgery for local relapse after definitive radiotherapy.
METHODS: Thirty patients who underwent salvage surgery with a simultaneous neck node dissection for a local relapse after definitive radiotherapy for HNSCC between 1992 and 2000 were included in this study. The primary tumor sites were oral cavity in six patients, oropharynx in 17, supraglottic larynx in three, and hypopharynx in four. Initially, seven patients had T2 disease, eight had T3, and 15 had T4.
RESULTS: Twelve patients (40%) experienced postoperative complications, including two deaths. There was no cervical lymph node metastasis (pN0) in 29 of the 30 patients. Fifteen patients (50%) had a recurrence after salvage surgery, including 11 new local recurrences and four patients with distant metastasis.
CONCLUSIONS: The risk of neck node metastasis during salvage surgery for local recurrence in patients treated initially with radiation for N0 HNSCC is low. Neck dissection should be performed in only limited area, depending on the surgical procedure used for tumor resection.
Keywords
Adult, Aged, Carcinoma, Squamous Cell/mortality, Carcinoma, Squamous Cell/radiotherapy, Female, Head and Neck Neoplasms/mortality, Head and Neck Neoplasms/radiotherapy, Humans, Lymph Node Excision/methods, Lymphatic Metastasis, Male, Middle Aged, Neck/surgery, Neoplasm Recurrence, Local/mortality, Neoplasm Recurrence, Local/surgery, Postoperative Complications/epidemiology, Postoperative Complications/mortality, Radiotherapy, Adjuvant, Retrospective Studies, Salvage Therapy, Time Factors, Treatment Outcome
Pubmed
Create date
01/12/2014 18:44
Last modification date
20/08/2019 16:08
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