Method for performing cerebral perfusion-weighted MRI in neonates

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Serval ID
serval:BIB_A277D7CE6175
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Method for performing cerebral perfusion-weighted MRI in neonates
Journal
Pediatric Radiology
Author(s)
Laswad T., Wintermark P., Alamo L., Moessinger A., Meuli R., Gudinchet F.
ISSN
0301-0449
Publication state
Published
Issued date
2009
Peer-reviewed
Oui
Volume
39
Number
3
Pages
260-264
Language
english
Abstract
Cerebral perfusion-weighted imaging (PWI) in neonates is known to be technically difficult and there are very few published studies on its use in preterm infants. In this paper, we describe one convenient method to perform PWI in neonates, a method only recently used in newborns. A device was used to manually inject gadolinium contrast material intravenously in an easy, quick and reproducible way. We studied 28 newborn infants, with various gestational ages and weights, including both normal infants and those suffering from different brain pathologies. A signal intensity-time curve was obtained for each infant, allowing us to build perfusion maps. This technique offered a fast and easy method to manually inject a bolus gadolinium contrast material, which is essential in performing PWI in neonates. Cerebral PWI is technically feasible and reproducible in neonates of various gestational age and with various pathologies.
Pubmed
Web of science
Open Access
Yes
Create date
28/01/2009 10:51
Last modification date
01/10/2019 6:19
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