Quality of life and self-esteem in 7-year-old children with familial high risk of schizophrenia or bipolar disorder: the Danish High Risk and Resilience Study-VIA 7-a population-based cohort study.

Details

Serval ID
serval:BIB_A256F587D524
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Quality of life and self-esteem in 7-year-old children with familial high risk of schizophrenia or bipolar disorder: the Danish High Risk and Resilience Study-VIA 7-a population-based cohort study.
Journal
European child & adolescent psychiatry
Author(s)
Ellersgaard D., Gregersen M., Ranning A., Haspang T.M., Christiani C., Hemager N., Burton B.K., Spang K.S., Søndergaard A., Greve A., Gantriis D., Jepsen JRM, Mors O., Plessen K.J., Nordentoft M., Thorup AAE
ISSN
1435-165X (Electronic)
ISSN-L
1018-8827
Publication state
Published
Issued date
06/2020
Peer-reviewed
Oui
Volume
29
Number
6
Pages
849-860
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
It is well established that children with familial high risk of schizophrenia (FHR-SZ) or bipolar disorder (FHR-BP) have a higher risk of developing mental disorders, however, little is known of to what degree the genetic and environmental vulnerabilities affect the quality of life and self-esteem of these children. We aimed to compare the quality of life and self-esteem between children with FHR-SZ or FHR-BP and controls. We used Danish nationwide registers to retrieve a cohort of 522 7-year-old children with FHR-SZ or FHR-BP and controls. Quality of life was assessed with the 'Health-related Quality of Life Screening Instrument', KIDSCREEN-27, and the scale 'Social Acceptance (Bullying)' from the KIDSCREEN-52. Self-esteem was assessed with the self-report scale 'I think I am'. Assessors were blind to familial risk status of the children. Children with FHR-SZ displayed lower levels of the general quality of life, as well as lower scores on the 'Psychological Well-being' scale and the 'School Environment' scale of the KIDSCREEN-27 compared with controls. Both children with FHR-SZ and FHR-BP reported more bullying victimization compared with controls. Children with FHR-SZ reported lower self-esteem on the total scale of 'I think I am', as well as on the 'Skills and talents', the 'Psychological well-being', and the 'Relationships with others' subscales compared with controls. The findings of lower quality of life and self-esteem in children with FHR-SZ together with more bullying victimization in both familial high-risk groups call for studies on low risk, early intervention strategies towards this group of vulnerable children.
Keywords
Bipolar Disorder/psychology, Child, Cohort Studies, Denmark, Female, Humans, Male, Netherlands, Quality of Life/psychology, Schizophrenia/physiopathology, Self Concept, Self Report, Bipolar disorder, Familial high risk, Quality of life, Schizophrenia, Self-esteem
Pubmed
Web of science
Create date
10/09/2019 9:58
Last modification date
26/08/2020 5:22
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