Pre-transplant Social Adaptability Index and clinical outcomes in renal transplantation: The Swiss Transplant Cohort study.
Details
State: Public
Version: Author's accepted manuscript
License: All rights reserved
Serval ID
serval:BIB_A1F00A6FCAA4
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Pre-transplant Social Adaptability Index and clinical outcomes in renal transplantation: The Swiss Transplant Cohort study.
Journal
Clinical transplantation
Working group(s)
Psychosocial Interest Group, Swiss Transplant Cohort Study
Contributor(s)
Brack G., Büttiker A., Künzler P., Leppla L., Ribaut J., Boehler A., Koller M., Beerli N., Mauthner O., Berben L., Merçay A., Hadaya K., Seiler A., Dreifuss J.L., Künzler-Heule P., Burkhalter H., Struker M., Rothlisberger C., Struker M., Amico P., Axel A., Aubert J.D., Banz V., Beldi G., Benden C., Berger C., Bochud P.Y., Branca S., Bucher H., Carrel T., Catana E., Chalandon Y., de Rougemont O., Dickenmann M., Dreifuss J.L., Duchosal M., Fehr T., Ferrari-Lacraz S., Garzoni C., Gasche-Soccal P., Gaudet C., Giostra E., Golshayan D., Hadaya K., Halter J., Hauri D., Heim D., Hess C., Hillinger S., Hirsch H., Hirt P., Hofbauer G., Immer F., Koller M., Laesser B., Lang B., Lehmann R., Leichtle A., Lovis C., Manuel O., Marti H.P., Martin P.Y., Martinelli M., Mellac K., Merçay A., Mettler K., Meylan P., Mueller N., Müller A., Müller T., Müller-Arndt U., Müllhaupt B., Nägeli M., Pascual M., Posfay-Barbe K., Rick J., Rosselet A., Rossi S., Rothlin S., Ruschitzka F., Schanz U., Schaub S., Schnyder A., Schuurmans M., Simonetta F., Staufer K., Stampf S., Steiger J., Stirnimann G., Toso C., Van Delden C., Venetz J.P., Villard J., Wick M., Wilhlem M., Yerly P.
ISSN
1399-0012 (Electronic)
ISSN-L
0902-0063
Publication state
Published
Issued date
04/2021
Peer-reviewed
Oui
Volume
35
Number
4
Pages
e14218
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Publication Status: ppublish
Abstract
The impact of pre-transplant social determinants of health on post-transplant outcomes remains understudied. In the United States, poor clinical outcomes are associated with underprivileged status, as assessed by the Social Adaptability Index (SAI), a composite score of education, employment status, marital status, household income, and substance abuse. Using data from the Swiss Transplant Cohort Study (STCS), we determined the SAI's predictive value regarding two post-transplant outcomes: all-cause mortality and return to dialysis.
Between 2012 and 2018, we included adult renal transplant patients (aged ≥ 18 years) with pre-transplant assessment SAI scores, calculated from a STCS Psychosocial Questionnaire. Time to all-cause mortality and return to dialysis were predicted using Cox regression.
Of 1238 included patients (mean age: 53.8 ± 13.2 years; 37.9% female; median follow-up time: 4.4 years [IQR: 2.7]), 93 (7.5%) died and 57 (4.6%) returned to dialysis. The SAI's hazard ratio was 0.94 (95%CI: 0.88-1.01; p = .09) for mortality and 0.93 (95%CI: 0.85-1.02; p = .15) for return to dialysis.
In contrast to most published studies on social deprivation, analysis of this Swiss sample detected no significant association between SAI score and mortality or return to dialysis.
Between 2012 and 2018, we included adult renal transplant patients (aged ≥ 18 years) with pre-transplant assessment SAI scores, calculated from a STCS Psychosocial Questionnaire. Time to all-cause mortality and return to dialysis were predicted using Cox regression.
Of 1238 included patients (mean age: 53.8 ± 13.2 years; 37.9% female; median follow-up time: 4.4 years [IQR: 2.7]), 93 (7.5%) died and 57 (4.6%) returned to dialysis. The SAI's hazard ratio was 0.94 (95%CI: 0.88-1.01; p = .09) for mortality and 0.93 (95%CI: 0.85-1.02; p = .15) for return to dialysis.
In contrast to most published studies on social deprivation, analysis of this Swiss sample detected no significant association between SAI score and mortality or return to dialysis.
Keywords
Adult, Aged, Cohort Studies, Ethnicity, Female, Humans, Kidney Transplantation, Male, Middle Aged, Renal Dialysis, Switzerland/epidemiology, graft survival, kidney transplantation, mortality, socioeconomic factors
Pubmed
Web of science
Create date
26/01/2024 13:28
Last modification date
13/08/2024 6:57
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