Supracricoid partial laryngectomy with cricohyoidoepiglottopexy in patients with radiation therapy failure.

Details

Serval ID
serval:BIB_A1705AD23E13
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Supracricoid partial laryngectomy with cricohyoidoepiglottopexy in patients with radiation therapy failure.
Journal
World Journal of Surgical Oncology
Author(s)
Luna-Ortiz Kuauhyama, Pasche Philippe, Tamez-Velarde Mario, Villavicencio-Valencia Veronica
ISSN
1477-7819[electronic]
Publication state
Published
Issued date
2009
Volume
7
Pages
101
Language
english
Abstract
BACKGROUND: To assess functional results, complications, and success of larynx preservation in patients with recurrent squamous cell carcinoma after radiotherapy. METHODS: From a database of 40 patients who underwent supracricoid partial laryngectomy (SCPL) with cricohyoidoepiglottopexy (CHEP) from June 2001 to April 2006, eight patients were treated previously with radiotherapy due to squamous cell carcinoma of the glottic region and were treated for recurrence at the site of the primary cancer. RESULTS: SCPL with CHEP was performed in six men and two women with a mean age of 67 years due to recurrence and/or persistence at a mean time of 30 months postradiotherapy (in case #8 after concomitant chemoradiotherapy). Bilateral neck dissection at levels II-V was performed in six patients. Only case #8 presented metastasis in one node. In case #5, Delphian node was positive. It was possible to preserve both arytenoids in five cases. Definitive surgical margins were negative. Complications were encountered in seven patients. Follow-up was on average 44 months (range: 20-67 months). Organ preservation in this series was 75%, and local control was 87%. Overall 5-year survival was 50%. CONCLUSIONS: In selected patient with persistence and/or recurrence after radiotherapy due to cancer of the larynx, SCPL with CHEP seems to be feasible with acceptable local control and toxicity. Complications may occur as in previously non-irradiated patients. These complications must be treated conservatively to avoid altering laryngeal function.
Keywords
Glottic Carcinoma, Salvage Surgery, Surgical Salvage, Radiotherapy, Cancer
Pubmed
Web of science
Open Access
Yes
Create date
26/01/2010 12:19
Last modification date
20/08/2019 15:07
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