Reusability of filtering facepiece respirators after decontamination through drying and germicidal UV irradiation.

Details

Ressource 1Download: e003110.full.pdf (556.00 [Ko])
State: Public
Version: Final published version
License: CC BY-NC 4.0
Serval ID
serval:BIB_A06FF4915219
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Reusability of filtering facepiece respirators after decontamination through drying and germicidal UV irradiation.
Journal
BMJ global health
Author(s)
Vernez D., Save J., Oppliger A., Concha-Lozano N., Hopf N.B., Niculita-Hirzel H., Resch G., Michaud V., Dorange-Pattoret L., Charrière N., Batsungnoen K., Suarez G.
ISSN
2059-7908 (Print)
ISSN-L
2059-7908
Publication state
Published
Issued date
10/2020
Peer-reviewed
Oui
Volume
5
Number
10
Pages
e003110
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
During pandemics, such as the SARS-CoV-2, filtering facepiece respirators plays an essential role in protecting healthcare personnel. The recycling of respirators is possible in case of critical shortage, but it raises the question of the effectiveness of decontamination as well as the performance of the reused respirators.
Disposable respirators were subjected to ultraviolet germicidal irradiation (UVGI) treatment at single or successive doses of 60 mJ/cm <sup>2</sup> after a short drying cycle (30 min, 70°C). The germicidal efficacy of this treatment was tested by spiking respirators with two staphylococcal bacteriophages (vB_HSa_2002 and P66 phages). The respirator performance was investigated by the following parameters: particle penetration (NaCl aerosol, 10-300 nm), scanning electron microscopy (SEM), Fourier-transform infrared spectroscopy (FTIR), differential scanning calorimetry and mechanical tensile tests.
No viable phage particles were recovered from any of the respirators after decontamination (log reduction in virus titre >3), and no reduction in chemical or physical properties (SEM, particle penetrations <5%-6%) were observed. Increasing the UVGI dose 10-fold led to chemical alterations of the respirator filtration media (FTIR) but did not affect the physical properties (particle penetration), which was unaltered even at 3000 mJ/cm <sup>2</sup> (50 cycles). When respirators had been used by healthcare workers and undergone decontamination, they had particle penetration significantly greater than never donned respirators.
This decontamination procedure is an attractive method for respirators in case of shortages during a SARS pandemic. A successful implementation requires a careful design and particle penetration performance control tests over the successive reuse cycles.
Keywords
Betacoronavirus, Coronavirus Infections/prevention & control, Decontamination/methods, Equipment Contamination/prevention & control, Equipment Failure Analysis, Equipment Reuse, Humans, Infection Control/methods, Materials Testing, Pandemics/prevention & control, Pneumonia, Viral/prevention & control, Respiratory Protective Devices, Ultraviolet Rays, SARS, prevention strategies, public health
Pubmed
Web of science
Open Access
Yes
Create date
23/10/2020 12:27
Last modification date
24/11/2020 9:42
Usage data