Functional insights from the GC-poor genomes of two aphid parasitoids, Aphidius ervi and Lysiphlebus fabarum.

Details

Serval ID
serval:BIB_9FC80603D447
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Functional insights from the GC-poor genomes of two aphid parasitoids, Aphidius ervi and Lysiphlebus fabarum.
Journal
BMC genomics
Author(s)
Dennis A.B., Ballesteros G.I., Robin S., Schrader L., Bast J., Berghöfer J., Beukeboom L.W., Belghazi M., Bretaudeau A., Buellesbach J., Cash E., Colinet D., Dumas Z., Errbii M., Falabella P., Gatti J.L., Geuverink E., Gibson J.D., Hertaeg C., Hartmann S., Jacquin-Joly E., Lammers M., Lavandero B.I., Lindenbaum I., Massardier-Galata L., Meslin C., Montagné N., Pak N., Poirié M., Salvia R., Smith C.R., Tagu D., Tares S., Vogel H., Schwander T., Simon J.C., Figueroa C.C., Vorburger C., Legeai F., Gadau J.
ISSN
1471-2164 (Electronic)
ISSN-L
1471-2164
Publication state
Published
Issued date
29/05/2020
Peer-reviewed
Oui
Volume
21
Number
1
Pages
376
Language
english
Notes
Publication types: Journal Article
Publication Status: epublish
Abstract
Parasitoid wasps have fascinating life cycles and play an important role in trophic networks, yet little is known about their genome content and function. Parasitoids that infect aphids are an important group with the potential for biological control. Their success depends on adapting to develop inside aphids and overcoming both host aphid defenses and their protective endosymbionts.
We present the de novo genome assemblies, detailed annotation, and comparative analysis of two closely related parasitoid wasps that target pest aphids: Aphidius ervi and Lysiphlebus fabarum (Hymenoptera: Braconidae: Aphidiinae). The genomes are small (139 and 141 Mbp) and the most AT-rich reported thus far for any arthropod (GC content: 25.8 and 23.8%). This nucleotide bias is accompanied by skewed codon usage and is stronger in genes with adult-biased expression. AT-richness may be the consequence of reduced genome size, a near absence of DNA methylation, and energy efficiency. We identify missing desaturase genes, whose absence may underlie mimicry in the cuticular hydrocarbon profile of L. fabarum. We highlight key gene groups including those underlying venom composition, chemosensory perception, and sex determination, as well as potential losses in immune pathway genes.
These findings are of fundamental interest for insect evolution and biological control applications. They provide a strong foundation for further functional studies into coevolution between parasitoids and their hosts. Both genomes are available at https://bipaa.genouest.org.
Keywords
Animals, Aphids/genetics, Aphids/immunology, DNA Methylation/genetics, GC Rich Sequence, Genomics, Insect Proteins/genetics, Sex Determination Processes/genetics, Venoms/genetics, Wasps/genetics, Wasps/immunology, Aphid host, Aphidius ervi, Chemosensory genes, DNA methylation loss, GC content, Lysiphlebus fabarum, Parasitoid wasp, Toll and Imd pathways, Venom proteins, de novo genome assembly
Pubmed
Web of science
Open Access
Yes
Create date
10/06/2020 21:41
Last modification date
02/03/2021 7:27
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