In-vitro activity of temafloxacin for gram-positive pathogens.

Details

Ressource 1Download: serval:BIB_9FC148540F13.P001 (197.21 [Ko])
State: Public
Version: author
License: Not specified
It was possible to publish this article open access thanks to a Swiss National Licence with the publisher.
Serval ID
serval:BIB_9FC148540F13
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
In-vitro activity of temafloxacin for gram-positive pathogens.
Journal
The Journal of Antimicrobial Chemotherapy
Author(s)
Bille J., Glauser M.P.
ISSN
0305-7453
Publication state
Published
Issued date
12/1991
Peer-reviewed
Oui
Volume
28 Suppl C
Pages
9-14
Language
english
Notes
Publication types: Comparative Study ; Journal Article
Abstract
The antimicrobial activity of temafloxacin against aerobic Gram-positive cocci was compared to that of ciprofloxacin, ofloxacin, fleroxacin and pefloxacin using the broth microdilution technique. Temafloxacin was more active than the other four fluoroquinolones, particularly for viridans streptococci and Streptococcus pneumoniae. The MIC90 of temafloxacin was at least four-fold lower than that of ciprofloxacin and ofloxacin for viridans streptococci and penicillin-susceptible pneumococci. The MIC50s and MIC90s of temafloxacin were equal to or lower than those of the other fluoroquinolones for methicillin-susceptible Staphylococcus aureus (MSSA), methicillin-resistant S. aureus (MRSA), and methicillin-susceptible and methicillin-resistant coagulase-negative staphylococci. Temafloxacin was more active against all the other Gram-positive aerobes (except Enterococcus faecalis) tested than the other fluoroquinolones.
Keywords
Anti-Infective Agents/pharmacology, Fluoroquinolones, Gram-Positive Bacteria/drug effects, Quinolones/pharmacology
Pubmed
Web of science
Open Access
Yes
Create date
11/02/2008 12:39
Last modification date
01/10/2019 6:19
Usage data