Pneumopathie organisee cryptogenique ou secondaire.

Details

Serval ID
serval:BIB_9EFBC94F1915
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Title
Pneumopathie organisee cryptogenique ou secondaire.
Journal
Revue du Praticien
Author(s)
Lazor  R.
ISSN
0035-2640
Publication state
Published
Issued date
12/2007
Volume
57
Number
20
Pages
2243-8
Notes
English Abstract
Journal Article
Review
Abstract
Organising pneumonia is an inflammatory and fibroproliferative reaction of the lung, which gives rise to a clinico-pathological syndrome. It may occur without any detectable cause (cryptogenic organising pneumonia) or may be associated with various processes such as infections, drug toxicities, connective tissue disorders, etc. (secondary organising pneumonia). The clinical picture is usually subacute and includes fever, fatigue, weight loss, cough, dyspnea, crackles, and elevated inflammatory markers. At imaging, the most typical pattern consists of multiple subpleural consolidations. Bronchoalveolar lavage reveals a mixed alveolitis with lymphocytes and polymorphonuclear cells. Lung biopsy shows buds of loose connective tissue filling the lung alveoli. The diagnosis is made by combination of clinical, imaging and histopathological criteria. Most patients respond very well to corticosteroid therapy. Relapses are common but can usually be controlled with moderate doses of prednisone, and do not worsen the prognosis.
Keywords
Adrenal Cortex Hormones/therapeutic use Bronchiolitis Obliterans Organizing Pneumonia/*diagnosis/*drug therapy/epidemiology Diagnosis, Differential Diagnostic Imaging Humans
Pubmed
Create date
19/12/2008 11:58
Last modification date
20/08/2019 15:05
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