Normal myocardial perfusion assessed with multishot echo-planar imaging.

Details

Serval ID
serval:BIB_9E89CE4F008D
Type
Article: article from journal or magazin.
Collection
Publications
Title
Normal myocardial perfusion assessed with multishot echo-planar imaging.
Journal
Magnetic Resonance In Medicine
Author(s)
Schwitter J., Debatin J.F., von Schulthess G.K., McKinnon G.C.
ISSN
0740-3194 (Print)
ISSN-L
0740-3194
Publication state
Published
Issued date
1997
Volume
37
Number
1
Pages
140-147
Language
english
Abstract
A new magnetic resonance imaging strategy is presented for accessing myocardial perfusion. Most previous work has relied on using T1-weighted fast gradient-echo imaging to monitor dynamically the signal changes during the passage of a contrast media bolus. However, the gradient-echo approach is limited by an inability to image the entire heart with adequate temporal resolution. This paper focuses on a electrocardiogram-gated multishot echo-planar imaging sequence, using the simple strategy of using the intrinsic T1 weighting produced by a repetition time equal to the heart period. To quantitate the sequence's performance with respect to normal myocardial perfusion, seven volunteers were imaged, each with three different doses of the contrast medium gadolinium diethylenetriamine pentaacetic acid (Gd-DTPA). The first-pass dynamics of the contrast were quantified in 13 regions per heart for each examination. In all volunteers, the complete heart could be covered, with five to seven slices, every two heartbeats. Enhancement was homogeneous throughout the left ventricular myocardium, with an enhancement of approximately 50% for the optimum contrast dose of 0.05 mmol/kg Gd-DTPA.
Keywords
Adult, Contrast Media, Echo-Planar Imaging/methods, Electrocardiography, Female, Gadolinium DTPA, Heart/anatomy & histology, Humans, Image Processing, Computer-Assisted, Male, Organometallic Compounds/diagnostic use, Pentetic Acid/analogs & derivatives, Pentetic Acid/diagnostic use, Time Factors
Pubmed
Web of science
Create date
07/09/2011 19:33
Last modification date
20/08/2019 16:04
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