Prevalence of postmenopausal osteoporosis in Italy and validation of decision rules for referring women for bone densitometry.

Details

Serval ID
serval:BIB_9E39021537DF
Type
Article: article from journal or magazin.
Collection
Publications
Title
Prevalence of postmenopausal osteoporosis in Italy and validation of decision rules for referring women for bone densitometry.
Journal
Calcified tissue international
Author(s)
D'Amelio P., Spertino E., Martino F., Isaia G.C.
ISSN
1432-0827 (Electronic)
ISSN-L
0171-967X
Publication state
Published
Issued date
05/2013
Peer-reviewed
Oui
Volume
92
Number
5
Pages
437-443
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Abstract
We report the prevalence of osteoporosis, osteopenia, and fractures in a cohort of Italian women randomly recruited among the general population and validate the use of clinical guidelines in referring women for bone density testing. We enrolled in the study 995 healthy women (age range 45-92 years). A bone density test at the lumbar spine and femur was performed and a questionnaire on osteoporosis risk factors completed for all patients. The prevalence of osteoporosis was 33.67 %, that of osteopenia was 46.63, and 19.7 % were normal at bone density testing. Osteoporotic women were generally older and thinner, with a shorter period of estrogen exposure. The prevalence of fractures was 21.9 %, and fractured women had a lower bone density, were older, and had a longer postmenopausal period. Clinical guidelines for referring women for bone density testing performed poorly (the best performance was 68 %). This is the first study providing data on the prevalence of osteoporosis/osteopenia and of fractures in a cohort of healthy postmenopausal women. Known risk factors influence bone density and risk of fractures. The role of screening in detecting women with postmenopausal osteoporosis is far from optimal.
Keywords
Aged, Aged, 80 and over, Bone Density, Bone Diseases, Metabolic/pathology, Bone and Bones/pathology, Decision Making, Decision Support Systems, Clinical, Densitometry/methods, Estrogens/metabolism, Female, Humans, Italy/epidemiology, Middle Aged, Osteoporosis, Postmenopausal/epidemiology, Prevalence, Referral and Consultation, Risk Factors
Pubmed
Web of science
Create date
14/01/2020 8:01
Last modification date
15/01/2020 6:26
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