Pathological correlates of poststroke depression in elderly patients.

Details

Serval ID
serval:BIB_9E2923B8FFF3
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Pathological correlates of poststroke depression in elderly patients.
Journal
The American Journal of Geriatric Psychiatry
Author(s)
Bozikas V.P., Gold G., Kövari E., Herrmann F., Karavatos A., Giannakopoulos P., Bouras C.
ISSN
1064-7481
Publication state
Published
Issued date
2005
Peer-reviewed
Oui
Volume
13
Number
2
Pages
166-169
Language
english
Abstract
OBJECTIVE: The authors examined the relationship between poststroke depression and location of stroke. METHODS: They performed a clinicopathological analysis of 95 consecutively autopsied elderly initial-stroke survivors. RESULTS: The severity of brain vessel arteriosclerosis and frequency of brain vascular lesions were not significantly different between 21 cases with poststroke depression and 74 cases without. Earlier death was the only variable significantly associated with poststroke depression. No lesion pattern characterized the depression group. CONCLUSIONS: Neuropathological data confirm that depression is associated with worse prognosis in elderly stroke patients and lend support to the hypothesis that psychological rather than neurological factors are the main determinants of poststroke depression.
Keywords
Aged, Brain/blood supply, Brain/pathology, Depressive Disorder, Major/diagnosis, Depressive Disorder, Major/etiology, Diagnostic and Statistical Manual of Mental Disorders, Female, Humans, Male, Severity of Illness Index, Stroke/psychology
Pubmed
Web of science
Create date
10/03/2008 11:04
Last modification date
20/08/2019 15:04
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