Changes in quadratic phase coupling of EEG signals during wake and sleep in two chronic insomnia patients, before and after cognitive behavioral therapy

Details

Serval ID
serval:BIB_9DBCFBF238EA
Type
Article: article from journal or magazin.
Collection
Publications
Title
Changes in quadratic phase coupling of EEG signals during wake and sleep in two chronic insomnia patients, before and after cognitive behavioral therapy
Journal
Frontiers in Artificial Intelligence and Applications
Author(s)
Perrig  S., Dutoit  P., Espa-Cervena  K., Shaposhnyk  V., Pelletier  L., Berger  F., Villa  A. E. P.
ISSN
0922-6389
Publication state
Published
Issued date
2009
Peer-reviewed
Oui
Volume
204
Pages
217-228
Language
english
Notes
Perrig2009217
Abstract
Quantitative EEG studies of primary insomnia (PI) suggest that increased high frequency and reduction in slow frequency EEG activity could be associated with cortical "hyperarousal" and sleep homeostasis dysregulation. This preliminary study is the first to apply higher order EEG analysis in chronic PI patients. We analyzed phase coupling in two patients against two control subjects. We defined an index of resonant frequency (IRF) and show that both patients were characterized by high IRF values that suggest an increase in local cortical information processing before treatment. We show that cognitive behavioral therapy for insomnia (CBT-T) is able to reverse EEG phase coupling towards control values in as little as eight sessions. After treatment the patients were characterized by lower index values, thus suggesting recovery of information processing over wide-spread cortical areas.
Keywords
Insomnia, cognitive behavioral therapy, cortico-cortical resonances, bispectrum, bicoherence
Web of science
Create date
23/08/2010 16:52
Last modification date
20/08/2019 16:04
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