Tests génétiques préimplantatoires : enjeux légaux et éthiques dans la pratique clinique [Preimplantation genetic testing: legal and ethical aspects in clinical practice]

Details

Serval ID
serval:BIB_9D32B263CCEE
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Tests génétiques préimplantatoires : enjeux légaux et éthiques dans la pratique clinique [Preimplantation genetic testing: legal and ethical aspects in clinical practice]
Journal
Revue medicale suisse
Author(s)
Simon J.P., Pradervand P.A., Cina V., Superti-Furga A., Primi M.P., Leyvraz-Recrosio C., Fischer M., Vulliemoz N.
ISSN
1660-9379 (Print)
ISSN-L
1660-9379
Publication state
Published
Issued date
23/10/2019
Peer-reviewed
Oui
Volume
15
Number
668
Pages
1909-1913
Language
french
Notes
Publication types: English Abstract ; Journal Article
Publication Status: ppublish
Abstract
In Switzerland, since modifications of the law regulating reproductive medicine introduced the 1rst of September 2017, preimplantation genetic testing (PGT) has been legalised. Infertile couples undergoing in vitro fertilization (IVF) can benefit from this technology by detecting which embryos are aneuploid (ie abnormal number of chromosomes, PGT-A). This is performed in order to transfer euploid embryos (normal number of chromosomes) and to optimise success, though data are limited. Couples at risk of transmitting a severe monogenic disease or unbalanced translocation can undergo PGT for monogenic disease or chromosomal structural rearrangements (PGT-M/SR). These tests are subject to strict legal criteria. Their clinical application needs to be approved through a multidisciplinary approach taking into account legal and ethical issues while respecting the autonomy of the couples.
Pubmed
Create date
24/10/2019 15:53
Last modification date
05/11/2019 7:26
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