Comparing radiolytic production of H2O2 and development of Zebrafish embryos after ultra high dose rate exposure with electron and transmission proton beams.

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State: Public
Version: Final published version
License: CC BY 4.0
Serval ID
serval:BIB_9CD75B81043D
Type
Article: article from journal or magazin.
Collection
Publications
Institution
UNIL/CHUV
Title
Comparing radiolytic production of H2O2 and development of Zebrafish embryos after ultra high dose rate exposure with electron and transmission proton beams.
Journal
Radiotherapy and oncology
Author(s)
Kacem H., Psoroulas S., Boivin G., Folkerts M., Grilj V., Lomax T., Martinotti A., Meer D., Ollivier J., Petit B., Safai S., Sharma R.A., Togno M., Vilalta M., Weber D.C., Vozenin M.C.
ISSN
1879-0887 (Electronic)
ISSN-L
0167-8140
Publication state
Published
Issued date
10/2022
Peer-reviewed
Oui
Volume
175
Pages
197-202
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
Publication Status: ppublish
Abstract
The physico-chemical and biological response to conventional and UHDR electron and proton beams was investigated, along with conventional photons. The temporal structure and nature of the beam affected both, with electron beam at ≥1400 Gy/s and proton beam at 0.1 and 1260 Gy/s found to be isoefficient at sparing zebrafish embryos.
Keywords
Animals, Zebrafish, Proton Therapy, Electrons, Protons, Hydrogen Peroxide, Radiotherapy Dosage, Electron FLASH, Hydrogen peroxyde, Proton FLASH, Zebrafish embryos
URN
urn:nbn:ch:serval-BIB_9CD75B81043D8
OAI-PMH
oai:serval.unil.ch:BIB_9CD75B81043D
DOI
10.1016/j.radonc.2022.07.011
Pubmed
35868604
Web of science
000875662500007
Open Access
Yes
Create date
02/08/2022 13:32
Last modification date
22/06/2024 6:17
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