Risk of mental disorders in children of parents with alcohol or heroin dependence: a controlled high-risk study.

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State: Public
Version: author
Serval ID
serval:BIB_9C94B137472D
Type
Article: article from journal or magazin.
Collection
Publications
Title
Risk of mental disorders in children of parents with alcohol or heroin dependence: a controlled high-risk study.
Journal
European Addiction Research
Author(s)
Vidal S.I., Vandeleur C., Rothen S., Gholam-Rezaee M., Castelao E., Halfon O., Aubry J.M., Ferrero F., Preisig M.
ISSN
1421-9891 (Electronic)
ISSN-L
1022-6877
Publication state
Published
Issued date
2012
Peer-reviewed
Oui
Volume
18
Number
5
Pages
253-264
Language
english
Notes
Publication types: Journal Article Publication Status: ppublish
Abstract
Aim: To assess the specific effect of alcohol dependence (AD) or heroin dependence (HD) in patients and their spouses on the risk of psychopathology in their 276 6.0- to 17.9- year-old children (mean 11.3 years). Methods: The sample included 101 offspring of patients with AD, 23 of patients with HD, and 152 of medical controls, as well as their 2 parents. Participants were assessed using semistructured diagnostic interviews and family history reports by psychologists blind to patient diagnoses. Results: Children of HD and AD patients had largely elevated rates of recurrent major depressive disorder. Children of HD patients were also at an increased risk for attention deficit hyperactivity disorder and substance use disorders (SUD). There were interactions between SUD in the 2 parents to increase the risk of SUD in offspring. Conclusions: These results emphasize the need for prompt identification and treatment of these children and highlight the need to pay clinical attention not only to the patient, but also to the co-parent in order to optimize prevention in offspring.
Pubmed
Web of science
Open Access
Yes
Create date
27/08/2012 18:46
Last modification date
20/08/2019 16:03
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