High prevalence of osteoporosis in Swiss women aged 60 and older: a 2-year pilot screening campaign.


Serval ID
Inproceedings: an article in a conference proceedings.
Publication sub-type
Poster: Summary – with images – on one page of the results of a researche project. The summaries of the poster must be entered in "Abstract" and not "Poster".
High prevalence of osteoporosis in Swiss women aged 60 and older: a 2-year pilot screening campaign.
Title of the conference
AGS 2012, Annual Scientific Meeting of the American Geriatrics Society
Krieg M.A., Lamy O., Aubry-Rozier B., Stoll D., Hans D., Berthoud M.
Seattle, Washington, United-States, May 3-5, 2012
Publication state
Issued date
Journal of the American Geriatrics Society
Background: Osteoporosis (OP) is frequent in postmenopausal
women, but remains underdiagnosed and undertreated. In Switzerland,
DXA is not reimbursed by the insurances for screening, even if
it is recommended to test women's Bone Mineral Density (BMD) at
the age of 65.
Methods: To assess the feasibility of a screening program for OP,
the Bone diseases center of Lausanne has been mandated to perform
a 2-year information and screening campaign (3 days per months) for
women age 60 and older through the state of Vaud using a mobile
unit for bone assessment. This project is still ongoing.
Women are informed by media for dates and screening locations.
Appointments are taken by phone. Women known for osteoporosis
or already treated are excluded. During the evaluation every
women is assessed by a questionnaire for risk factors, by a DXA
measurement (Discovery C, Hololgic), and by Vertebral Fracture Assessment
(VFA) for Genant's grades 2 and 3 prevalent vertebral fractures
(VF). Women are considered at high risk of fracture if they have
a hip fracture, a VF, another fragility fracture with a BMD T-score ≤-2
or a BMD T-score ≤-2.5.
Results: After 17 months (50 days of screening), 752 women
were assessed, mean age 66±6 yrs, mean BMI 26±5 kg/m2, mean lowest
T-score -1.6±1.0 SD. 215 women (29%) were considered at high
risk, 92 of them (12%) having established OP and 50 (7%) having one
or more fragility VF. VF were unknown for 83% of the women and
discovered by VFA. The number needed to screen (NNS) were 3.5 for
high risk women, 8.2 for established OP and 15 for VF.
Conclusions: After near ¾ of the project, prevalence of women
at high risk of fracture was high, with a NNS below 4. Knowing the
global cost of OP and that current treatment have a high efficacy for
fracture risk reduction, such a screening program could have a positive
economic impact. VFA allowed discovering many women with
unknown VF, who were at very high risk of further fractures. A systematic
screening for VF should be added to BMD measurements
after the age of 60.
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30/01/2013 15:11
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20/08/2019 16:02
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