Ten-year single-centre experience in fertility preservation of 459 patients suffering from acute leukaemia.

Details

Serval ID
serval:BIB_9AD1D6CC6F77
Type
Article: article from journal or magazin.
Collection
Publications
Title
Ten-year single-centre experience in fertility preservation of 459 patients suffering from acute leukaemia.
Journal
British journal of haematology
Author(s)
Noetzli J., Voruz S., Wunder D., Primi M.P., Spertini O., Blum S.
ISSN
1365-2141 (Electronic)
ISSN-L
0007-1048
Publication state
Published
Issued date
03/2019
Peer-reviewed
Oui
Volume
184
Number
6
Pages
969-973
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
Acute leukaemia is a life-threatening disease that needs treatment without delay. Fertility preservation is recommended, but often not possible because of the necessity to start treatment as soon as possible. The present study is a retrospective single-centre analysis of 459 patients diagnosed with acute leukaemia between 2002 and 2012. Sperm or oocyte preservation was successfully performed in only 29 (6%) patients. Of the 150 children, no paediatric patient sample was taken. The collected samples enabled the conception of 2 children by in vitro fertilisation; in addition, 3 spontaneous, non-assisted births in partners of male patients were observed. Fertility preservation is important but difficult to accomplish in patients with acute leukaemia; more efforts are clearly needed to preserve fertility in long-term survivors of acute leukaemia.
Keywords
acute leukaemia, chemotherapy, fertility
Pubmed
Web of science
Create date
23/01/2019 11:05
Last modification date
20/08/2019 15:01
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