Inhibition of the anti-natriuretic action of aldosterone by thyroid hormone in the rat

Details

Serval ID
serval:BIB_9A51A476FE31
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Inhibition of the anti-natriuretic action of aldosterone by thyroid hormone in the rat
Journal
Pflügers Archiv : European Journal of Physiology
Author(s)
Diezi  J., Nenniger  M., Rossier  B. C.
ISSN
0031-6768
Publication state
Published
Issued date
05/1980
Peer-reviewed
Oui
Volume
385
Number
1
Pages
91-93
Notes
Journal Article
Abstract
Urinary sodium excretion was measured in adrenalectomized, euthyroid rats, within 4 hours after injection of aldosterone and/or thyroid hormone (T3). Rats which received both hormones excreted significantly more Na than rats injected with aldosterone alone. Reverse-T3 did not affect the antinatriuretic action of aldosterone. Natriuresis following injection of T3 alone was similar to that measured in the absence of exogenous hormones. These observations suggest an interaction between aldosterone and T3 on renal Na excretion.
Keywords
Aldosterone/*pharmacology *Aldosterone Antagonists Animals Male Natriuresis/*drug effects Rats Sodium/urine Triiodothyronine/*pharmacology
Pubmed
Web of science
Create date
24/01/2008 13:00
Last modification date
20/08/2019 15:01
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