Posterior linear stromal haze formation after simultaneous photorefractive keratectomy followed by corneal collagen cross-linking.

Details

Serval ID
serval:BIB_99E20600F1F0
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Posterior linear stromal haze formation after simultaneous photorefractive keratectomy followed by corneal collagen cross-linking.
Journal
Investigative ophthalmology & visual science
Author(s)
Kymionis G.D., Portaliou D.M., Diakonis V.F., Kontadakis G.A., Krasia M.S., Papadiamantis A.G., Coskunseven E., Pallikaris A.I.
ISSN
1552-5783 (Electronic)
ISSN-L
0146-0404
Publication state
Published
Issued date
10/2010
Peer-reviewed
Oui
Volume
51
Number
10
Pages
5030-5033
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
To report the development of posterior linear stromal haze after simultaneous photorefractive keratectomy (PRK) followed by corneal collagen cross-linking (CXL).
Combined simultaneous customized PRK followed by corneal collagen cross-linking was performed in 23 patients (28 eyes) with keratoconus. Corneas were examined biomicroscopically and by means of confocal microscopy before surgery and 1, 3, 6, 9, and 12 months after surgery.
Posterior linear stromal haze was observed clinically (slit lamp biomicroscopy) one month after surgery in 13 of 28 eyes (46.42%). No corneal edema or anterior haze formation was evident. Confocal microscopy revealed in those 13 eyes a hyperreflective area at the level of the posterior stroma 1 month after combined treatment. Both slit lamp examination and corneal confocal microscopy follow-up demonstrated a gradual anterior movement and a decrease in reflectance of this finding. At 12 months this posterior linear stromal haze, despite its anterior movement and decreased density, did not completely disappear at slit lamp and confocal microscopy analysis.
Posterior linear stromal haze formation may appear after simultaneous PRK followed by CXL in patients with keratoconus. This finding seems to gradually become less dense and slowly moves toward the anterior stroma.
Keywords
Adult, Collagen/metabolism, Combined Modality Therapy, Corneal Opacity/diagnosis, Corneal Opacity/etiology, Corneal Stroma/metabolism, Corneal Stroma/pathology, Corneal Topography, Cross-Linking Reagents, Female, Humans, Keratoconus/drug therapy, Keratoconus/surgery, Keratoconus/therapy, Lasers, Excimer/therapeutic use, Male, Microscopy, Confocal, Photochemotherapy, Photorefractive Keratectomy, Photosensitizing Agents/therapeutic use, Postoperative Complications, Ultraviolet Rays, Young Adult
Pubmed
Web of science
Open Access
Yes
Create date
01/10/2019 15:21
Last modification date
06/10/2019 5:26
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