Chirurgie bariatrique et psychotropes: où en sommes-nous? [Bariatric surgery and psychotropic drugs : where are we now ?]

Details

Serval ID
serval:BIB_99C3422E5AD0
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Chirurgie bariatrique et psychotropes: où en sommes-nous? [Bariatric surgery and psychotropic drugs : where are we now ?]
Journal
Revue medicale suisse
Author(s)
Vandenberghe F., Corminboeuf Y., Favre L.
ISSN
1660-9379 (Print)
ISSN-L
1660-9379
Publication state
Published
Issued date
20/03/2019
Peer-reviewed
Oui
Volume
15
Number
643
Pages
631-635
Language
french
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
Bariatric surgery is considered an effective treatment against obesity. This intervention and the subsequent weight loss can affect several pharmacokinetic parameters leading to a possible need of dosing adjustment. Despite an increasing number of bariatric interventions, clinical recommendations are often based on theoretical principles and expert opinions. Because reliable clinical and biological parameters for adjusting psychotropic drug are not available, the use of therapeutic drug monitoring needs to be advised as a useful approach. However, it is not currently possible to predict the effect of bariatric surgery on psychotropic blood levels, and due to their important inter-individual variability, preoperative medication blood levels should be measured to ensure an adequate postoperative dosing adaptation.
Keywords
Bariatric Surgery, Humans, Obesity, Morbid/surgery, Postoperative Period, Psychotropic Drugs/therapeutic use, Weight Loss
Pubmed
Create date
28/03/2019 10:13
Last modification date
29/10/2019 11:49
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