Intracellular membrane fusion: SNAREs only?

Details

Serval ID
serval:BIB_99A3C61735ED
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Title
Intracellular membrane fusion: SNAREs only?
Journal
Current Opinion in Cell Biology
Author(s)
Mayer A.
ISSN
0955-0674 (Print)
ISSN-L
0955-0674
Publication state
Published
Issued date
1999
Peer-reviewed
Oui
Volume
11
Number
4
Pages
447-452
Language
english
Abstract
The past two years have seen vigorous attempts to elucidate the mechanism driving intracellular membrane fusion. Much attention was focused on the role of SNARE complexes. Their crystal structure was solved and fusion was reconstituted using proteoliposomes with purified SNAREs suggesting them to be the minimal machinery for fusion. Work on physiological membranes, however, points in another direction and has spurred a hot debate on the function of SNAREs.
Keywords
Animals, Calcium/metabolism, Intracellular Membranes/physiology, Membrane Fusion/physiology, Membrane Proteins/metabolism, SNARE Proteins, Signal Transduction, Vesicular Transport Proteins
Pubmed
Web of science
Create date
24/01/2008 15:06
Last modification date
20/08/2019 15:01
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