HHV-8-negative multicentric Castleman disease presenting as a crescentic immune complexes membranoproliferative glomerulonephritis.

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Version: Author's accepted manuscript
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Serval ID
serval:BIB_992D4D3B538A
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Institution
Title
HHV-8-negative multicentric Castleman disease presenting as a crescentic immune complexes membranoproliferative glomerulonephritis.
Journal
BMJ case reports
Author(s)
Nunes M.B., Rotman S., Duss F.R., Halfon M.
ISSN
1757-790X (Electronic)
ISSN-L
1757-790X
Publication state
Published
Issued date
06/01/2020
Peer-reviewed
Oui
Volume
13
Number
1
Language
english
Notes
Publication types: Case Reports ; Journal Article
Publication Status: epublish
Abstract
Multicentric Castleman disease is a rare polyclonal lymphoproliferative disorder mainly associated with two renal manifestations: thrombotic microangiopathy and amyloidosis. Nevertheless, we report here a case of human herpes virus-8 negative multicentric Castleman disease with membranous proliferative glomerulonephritis and extracapillary proliferation. A patient was successfully treated with corticosteroids, anti-CD20 and cyclophosphamide therapy.
Keywords
Adrenal Cortex Hormones/therapeutic use, Antigen-Antibody Complex, Castleman Disease/complications, Castleman Disease/drug therapy, Cyclophosphamide/therapeutic use, Diagnosis, Differential, Drug Therapy, Combination, Glomerulonephritis, Membranoproliferative/drug therapy, Glomerulonephritis, Membranoproliferative/etiology, Herpesvirus 8, Human, Humans, Immunologic Factors/therapeutic use, Immunosuppressive Agents/therapeutic use, Male, Middle Aged, Rituximab/therapeutic use, acute renal failure, proteinurea
Pubmed
Open Access
Yes
Create date
10/01/2020 12:23
Last modification date
29/08/2020 6:20
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