The UniProt-GO Annotation database in 2011.

Details

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State: Public
Version: Final published version
Serval ID
serval:BIB_98BC9474447E
Type
Article: article from journal or magazin.
Collection
Publications
Title
The UniProt-GO Annotation database in 2011.
Journal
Nucleic Acids Research
Author(s)
Dimmer E.C., Huntley R.P., Alam-Faruque Y., Sawford T., O'Donovan C., Martin M.J., Bely B., Browne P., Mun Chan W., Eberhardt R., Gardner M., Laiho K., Legge D., Magrane M., Pichler K., Poggioli D., Sehra H., Auchincloss A., Axelsen K., Blatter M.C., Boutet E., Braconi-Quintaje S., Breuza L., Bridge A., Coudert E., Estreicher A., Famiglietti L., Ferro-Rojas S., Feuermann M., Gos A., Gruaz-Gumowski N., Hinz U., Hulo C., James J., Jimenez S., Jungo F., Keller G., Lemercier P., Lieberherr D., Masson P., Moinat M., Pedruzzi I., Poux S., Rivoire C., Roechert B., Schneider M., Stutz A., Sundaram S., Tognolli M., Bougueleret L., Argoud-Puy G., Cusin I., Duek-Roggli P., Xenarios I., Apweiler R.
ISSN
1362-4962 (Electronic)
ISSN-L
0305-1048
Publication state
Published
Issued date
2012
Volume
40
Number
Database issue
Pages
D565-D570
Language
english
Abstract
The GO annotation dataset provided by the UniProt Consortium (GOA: http://www.ebi.ac.uk/GOA) is a comprehensive set of evidenced-based associations between terms from the Gene Ontology resource and UniProtKB proteins. Currently supplying over 100 million annotations to 11 million proteins in more than 360,000 taxa, this resource has increased 2-fold over the last 2 years and has benefited from a wealth of checks to improve annotation correctness and consistency as well as now supplying a greater information content enabled by GO Consortium annotation format developments. Detailed, manual GO annotations obtained from the curation of peer-reviewed papers are directly contributed by all UniProt curators and supplemented with manual and electronic annotations from 36 model organism and domain-focused scientific resources. The inclusion of high-quality, automatic annotation predictions ensures the UniProt GO annotation dataset supplies functional information to a wide range of proteins, including those from poorly characterized, non-model organism species. UniProt GO annotations are freely available in a range of formats accessible by both file downloads and web-based views. In addition, the introduction of a new, normalized file format in 2010 has made for easier handling of the complete UniProt-GOA data set.
Keywords
Databases, Protein, Molecular Sequence Annotation/standards, Vocabulary, Controlled
Pubmed
Web of science
Open Access
Yes
Create date
25/01/2012 9:35
Last modification date
20/08/2019 15:00
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