Main Fetal Predictors of Adverse Neonatal Outcomes in Pregnancies with Gestational Diabetes Mellitus.

Details

Ressource 1Request a copy Under indefinite embargo.
UNIL restricted access
State: Public
Version: author
License: CC BY 4.0
Serval ID
serval:BIB_97ADD1248B07
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Main Fetal Predictors of Adverse Neonatal Outcomes in Pregnancies with Gestational Diabetes Mellitus.
Journal
Journal of clinical medicine
Author(s)
Antoniou M.C., Gilbert L., Gross J., Rossel J.B., Fumeaux CJF, Vial Y., Puder J.J.
ISSN
2077-0383 (Print)
ISSN-L
2077-0383
Publication state
Published
Issued date
28/07/2020
Peer-reviewed
Oui
Volume
9
Number
8
Language
english
Notes
Publication types: Journal Article
Publication Status: epublish
Abstract
The objectives of this study were to (a) assess the utility of fetal anthropometric variables to predict the most relevant adverse neonatal outcomes in a treated population with gestational diabetes mellitus (GDM) beyond the known impact of maternal anthropometric and metabolic parameters and (b) to identify the most important fetal predictors. A total of 189 patients with GDM were included. The fetal predictors included sonographically assessed fetal weight centile (FWC), FWC > 90% and <10%, and fetal abdominal circumference centile (FACC), FACC > 90% and < 10%, at 29 0/7 to 35 6/7 weeks. Neonatal outcomes comprising neonatal weight centile (NWC), large and small for gestational age (LGA, SGA), hypoglycemia, prematurity, hospitalization for neonatal complication, and (emergency) cesarean section were evaluated. Regression analyses were conducted. Fetal variables predicted anthropometric neonatal outcomes, prematurity, cesarean section and emergency cesarean section. These associations were independent of maternal anthropometric and metabolic predictors, with the exception of cesarean section. FWC was the most significant predictor for NWC, LGA and SGA, while FACC was the most significant predictor for prematurity and FACC > 90% for emergency cesarean section. In women with GDM, third-trimester fetal anthropometric parameters have an important role in predicting adverse neonatal outcomes beyond the impact of maternal predictors.
Keywords
fetal anthropometry, fetal ultrasound, gestational diabetes, neonatal complications, pregnancy outcomes
Pubmed
Web of science
Open Access
Yes
Funding(s)
Swiss National Science Foundation / Projects
Create date
13/08/2020 8:06
Last modification date
04/12/2020 6:26
Usage data