The cartilage of the lower limb joints is exposed to high levels of mechanical stress and therefore is a frequent site of degenerative and traumatic lesions. Magnetic resonance imaging (MRI) is the modality of choice for the assessment of these cartilage lesions. To date, clinically available sequences have focused on morphological defects and cartilage loss. Efforts have been made in recent years to depict cartilage lesions at an earlier stage, with new quantitative sequences focusing on the biochemical assessment of tissue.After a brief review of the hyaline cartilage structure, we review the current morphological imaging methods and the biochemical MRI techniques to assess the cartilage. We then illustrate the application of these MRI sequences for the most common degenerative and traumatic disorders affecting lower limb cartilage.