Prevalence of FMR1 repeat expansions in movement disorders. A systematic review.

Details

Serval ID
serval:BIB_9606854A55B0
Type
Article: article from journal or magazin.
Collection
Publications
Title
Prevalence of FMR1 repeat expansions in movement disorders. A systematic review.
Journal
Neuroepidemiology
Author(s)
Hall D.A., Hagerman R.J., Hagerman P.J., Jacquemont S., Leehey M.A.
ISSN
0251-5350 (Print)
ISSN-L
0251-5350
Publication state
Published
Issued date
2006
Peer-reviewed
Oui
Volume
26
Number
3
Pages
151-155
Language
english
Notes
Publication types: Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Review
Publication Status: ppublish
Abstract
We reviewed prevalence rates of fragile X mental retardation gene (FMR1) repeat expansions in movement disorder populations. Inclusion criteria included published epidemiological studies from systematic searches of Medline, Pubmed, Cochrane Databases and Web Science. Thirteen cross-sectional studies were carried out between 2003 and 2005. Subjects with ataxia showed higher than expected rates while those with essential tremor and parkinsonism showed lower rates. The heterogeneous design of the studies, inclusion criteria and mean age of subjects may have led to underestimation of FMR1 repeat expansion prevalence rates.

Keywords
Cross-Sectional Studies, DNA Repeat Expansion/genetics, Female, Fragile X Mental Retardation Protein/genetics, Humans, Male, Middle Aged, Movement Disorders/genetics
Pubmed
Web of science
Create date
28/02/2008 10:42
Last modification date
20/08/2019 14:58
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