Immunologie de la sarcoidose. [Immunology of sarcoidosis]
Details
Serval ID
serval:BIB_9533ED7B3811
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Immunologie de la sarcoidose. [Immunology of sarcoidosis]
Journal
Schweizerische Medizinische Wochenschrift
ISSN
0036-7672 (Print)
Publication state
Published
Issued date
07/1981
Volume
111
Number
29
Pages
1066-75
Notes
English Abstract
Journal Article --- Old month value: Jul 18
Journal Article --- Old month value: Jul 18
Abstract
The sarcoid granulomas and the preceding mononuclear infiltration are composed of immunologically activated cells. Hyperactivity of circulating B cells and the frequent impairment of cell-mediated hypersensitivity could be due to an imbalance between T cell sub-populations. Kveim-Siltzbach test positivity and demonstration of circulating antibodies specifically directed against a sarcoid spleen extract suggest that this extract could have antigenic properties. Cell populations yielded by broncho-alveolar lavage in patients with hypersensitivity pneumonitis or with respiratory sarcoidosis are closely related. It is conceivable that sarcoidosis could result from some inhaled agent(s) which induce a self-perpetuating immunologic response of indeterminate duration. The relevance of immunological studies on sarcoidosis for medical practice is summarized.
Keywords
Alveolitis, Extrinsic Allergic/immunology
Antibody Formation
Humans
Immune Complex Diseases/immunology
Immunity, Cellular
Kveim Test
Lung/immunology
Lymphocytes/immunology
Sarcoidosis/diagnosis/etiology/*immunology
Pubmed
Web of science
Create date
25/01/2008 10:50
Last modification date
20/08/2019 15:57