Syncope in patients with pulmonary embolism: comparison between patients with syncope as the presenting symptom of pulmonary embolism and patients with pulmonary embolism without syncope

Details

Serval ID
serval:BIB_9510AF8A0911
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Syncope in patients with pulmonary embolism: comparison between patients with syncope as the presenting symptom of pulmonary embolism and patients with pulmonary embolism without syncope
Journal
Vascular Medicine
Author(s)
Castelli  R., Tarsia  P., Tantardini  C., Pantaleo  G., Guariglia  A., Porro  F.
ISSN
1358-863X (Print)
Publication state
Published
Issued date
11/2003
Volume
8
Number
4
Pages
257-61
Notes
Comparative Study
Journal Article --- Old month value: Nov
Abstract
Syncope as an initial presentation of pulmonary embolism occurs in 10% of patients. We compared clinical and instrumental parameters in patients with syncope as the presenting symptom of pulmonary embolism and in patients with documented pulmonary embolism without syncope. Seventy patients with the diagnosis of pulmonary embolism and apparently stable clinical conditions were evaluated. They were divided in two groups: 10 patients with syncope as the presenting symptom of pulmonary embolism (group 1) and 60 patients without syncope (group 2). Patients with syncope showed a more pronounced tendency to present with main pulmonary artery embolus than patients without syncope (contingency coefficient = 0.301, p < 0.04; one-tailed). However, despite the evidence that patients with syncope have significant reductions in systolic and/or diastolic blood pressure, shock was not observed in any patient. In no case was thrombolytic treatment given and all patients received standard anticoagulation with unfractioned heparin and oral anticoagulant. We suggest that syncope in the setting of non-massive pulmonary embolism may be due to vaso-vagal mechanism that can lead to a reduction of arterial blood pressure when central artery thrombosis is involved.
Keywords
Aged Anticoagulants/therapeutic use Cardiomegaly/ultrasonography Echocardiography Female Heart Atria/pathology Heparin/therapeutic use Humans Hypertrophy, Left Ventricular/ultrasonography Male Pulmonary Embolism/complications/*diagnosis/drug therapy Syncope/*etiology Thromboembolism/ultrasonography
Pubmed
Web of science
Open Access
Yes
Create date
25/01/2008 16:13
Last modification date
20/08/2019 15:57
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