A selective culture medium for screening linezolid-resistant gram-positive bacteria.
Details
Serval ID
serval:BIB_94C3DFC73C78
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
A selective culture medium for screening linezolid-resistant gram-positive bacteria.
Journal
Diagnostic microbiology and infectious disease
ISSN
1879-0070 (Electronic)
ISSN-L
0732-8893
Publication state
Published
Issued date
09/2019
Peer-reviewed
Oui
Volume
95
Number
1
Pages
1-4
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Publication Status: ppublish
Abstract
The SuperLinezolid medium was developed for screening resistance to linezolid (LZD) in Gram-positive bacteria (Staphylococcus spp., Enterococcus spp.). It was evaluated using LZD-susceptible (n = 20) and LZD-resistant (n = 17) Gram-positive isolates. The sensitivity was found to be 82% at 24 h (3 out of 17 isolates being missed), and reached 100% at 48 h. At 48 h, a single LZD-susceptible isolate grew (specificity 95%). By testing stools spiked with LZD-resistant Gram-positive strains, an excellent performance of the medium was observed, with a lowest detection limit ranging from 10 <sup>1</sup> to 10 <sup>2</sup> CFU/ml. Overall, this medium is accurate for detection of LZD-resistant Gram-positive isolates after 24 h of culture.
Keywords
Anti-Bacterial Agents/analysis, Anti-Bacterial Agents/pharmacology, Bacteriological Techniques/methods, Culture Media/chemistry, Drug Resistance, Bacterial, Enterococcus/drug effects, Enterococcus/isolation & purification, Feces/microbiology, Gram-Positive Bacteria/drug effects, Gram-Positive Bacteria/isolation & purification, Humans, Linezolid/analysis, Linezolid/pharmacology, Microbial Sensitivity Tests, Sensitivity and Specificity, Staphylococcus/drug effects, Staphylococcus/isolation & purification, Antibiotic, Enterococci, Linezolid, Screening, Staphylococci
Pubmed
Web of science
Create date
23/05/2024 13:36
Last modification date
24/05/2024 7:05
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